decreased single-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<5AT161>/Themis<5AT161>

http://metadb.riken.jp/0008083I129SSvEvC57BL6DBA2Rag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY71VboThemis5AT161Themis5AT161Themis5AT161TgTcraHYTcrbHY71VboRag2tm1Fwa

decreased single-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<5AT161>/Themis<5AT161>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thymocyte selection associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443552
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?,Themis<5AT161>/Themis<5AT161>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Themis<5AT161>|Tg(TcraH-Y,TcrbH-Y)71Vbo|Rag2<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased single-positive T cell number
  http://purl.obolibrary.org/obo/MP_0008083

文献

http://purl.org/net/cito/citesAsAuthority

• Andy L. Johnson, et.al., Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19597497