decreased Langerhans cell number_Tgfb1<tm2Flv>/B9d2/Tgfb1<tm1Flv>,Tg(CD207-cre)1Dhka/?

http://metadb.riken.jp/0008119I129S6SvEvTacC57BL6JSJLJTgfb1tm2FlvB9d2Tgfb1tm1FlvTgCD207cre1DhkaTgCD207cre1DhkaTgfb1tm2FlvB9d2Tgfb1tm1Flv

decreased Langerhans cell number_Tgfb1<tm2Flv>/B9d2/Tgfb1<tm1Flv>,Tg(CD207-cre)1Dhka/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Daniel H Kaplan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761648
• transforming growth factor, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98725

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tgfb1<tm2Flv>/B9d2/Tgfb1<tm1Flv>,Tg(CD207-cre)1Dhka/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD207-cre)1Dhka|Tgfb1<tm2Flv>|B9d2/Tgfb1<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Langerhans cell number
  http://purl.obolibrary.org/obo/MP_0008119

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel H. Kaplan, et.al., Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17938236