decreased Langerhans cell number_Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Tg(CD207-cre)1Dhka/?

http://metadb.riken.jp/0008119I129S6SvEvTacC57BL6JSJLJTgfbr2tm12HlmTgfbr2tm12HlmTgCD207cre1DhkaTgfbr2tm12HlmTgCD207cre1Dhka

decreased Langerhans cell number_Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Tg(CD207-cre)1Dhka/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729
• transgene insertion 1, Daniel H Kaplan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761648

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Tg(CD207-cre)1Dhka/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr2<tm1.2Hlm>|Tg(CD207-cre)1Dhka

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Langerhans cell number
  http://purl.obolibrary.org/obo/MP_0008119

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel H. Kaplan, et.al., Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17938236