decreased B-1a cell number_Cd22<tm1Lam>/Cd22<tm1Lam>,Igh<tm1.2Rsky>/Igh<tm1.2Rsky>

http://metadb.riken.jp/0008168I129BALBcC57BL6Cd22tm1LamCd22tm1LamIghtm12RskyIghtm12RskyIghtm12RskyCd22tm1Lam

decreased B-1a cell number_Cd22<tm1Lam>/Cd22<tm1Lam>,Igh<tm1.2Rsky>/Igh<tm1.2Rsky>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• CD22 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88322

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd22<tm1Lam>/Cd22<tm1Lam>,Igh<tm1.2Rsky>/Igh<tm1.2Rsky>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm1.2Rsky>|Cd22<tm1Lam>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1a cell number
  http://purl.obolibrary.org/obo/MP_0008168

文献

http://purl.org/net/cito/citesAsAuthority

• Ari. Waisman, et.al., IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17420268