decreased B-1a cell number_Igll1<tm1Shim>/Igll1<tm1Shim>,Vpreb1<tm1Shim>/Vpreb1<tm1Shim>,Vpreb2<tm1Shim>/Vpreb2<tm1Shim>

http://metadb.riken.jp/0008168I129P2OlaHsdC57BL6Igll1tm1ShimIgll1tm1ShimVpreb1tm1ShimVpreb1tm1ShimVpreb2tm1ShimVpreb2tm1ShimIgll1tm1ShimVpreb1tm1ShimVpreb2tm1Shim

decreased B-1a cell number_Igll1<tm1Shim>/Igll1<tm1Shim>,Vpreb1<tm1Shim>/Vpreb1<tm1Shim>,Vpreb2<tm1Shim>/Vpreb2<tm1Shim>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pre-B lymphocyte gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:98937
• immunoglobulin lambda-like polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96529
• pre-B lymphocyte gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98936

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igll1<tm1Shim>/Igll1<tm1Shim>,Vpreb1<tm1Shim>/Vpreb1<tm1Shim>,Vpreb2<tm1Shim>/Vpreb2<tm1Shim>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igll1<tm1Shim>|Vpreb1<tm1Shim>|Vpreb2<tm1Shim>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1a cell number
  http://purl.obolibrary.org/obo/MP_0008168

文献

http://purl.org/net/cito/citesAsAuthority

• Takeyuki. Shimizu, et.al., VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus., Journal of immunology (Baltimore, Md. : 1950), 2002, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/12055243