decreased B-1a cell number_Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tab3<tm1Aki>/Tab3<tm1Aki>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0008168I129P2OlaHsdC57BL6Tab2tm21AkiTab2tm21AkiTab3tm1AkiTab3tm1AkiCd19tm1creCgnCd19Tab3tm1AkiCd19tm1creCgnTab2tm21AkiCd19

decreased B-1a cell number_Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tab3<tm1Aki>/Tab3<tm1Aki>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• TGF-beta activated kinase 1/MAP3K7 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915902
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• TGF-beta activated kinase 1/MAP3K7 binding protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913974

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tab2<tm2.1Aki>/Tab2<tm2.1Aki>,Tab3<tm1Aki>/Tab3<tm1Aki>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tab3<tm1Aki>|Cd19<tm1(cre)Cgn>|Tab2<tm2.1Aki>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1a cell number
  http://purl.obolibrary.org/obo/MP_0008168

文献

http://purl.org/net/cito/citesAsAuthority

• Daisuke. Ori, et.al., Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs., Journal of immunology (Baltimore, Md. : 1950), 2013, 190
  http://rdf.ncbi.nlm.nih.gov/pubmed/23509369