decreased B-1a cell number_Sh3kbp1<tm1Kuro>/Sh3kbp1<tm1Kuro>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/?

http://metadb.riken.jp/0008168IBALBcC57BL6NZBSh3kbp1tm1KuroSh3kbp1tm1KuroCd79atm1creRethCd79aGtROSA26Sortm4IkbkbRskyCd79aGtROSA26Sortm4IkbkbRskySh3kbp1tm1KuroCd79atm1creReth

decreased B-1a cell number_Sh3kbp1<tm1Kuro>/Sh3kbp1<tm1Kuro>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• SH3-domain kinase binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889583
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh3kbp1<tm1Kuro>/Sh3kbp1<tm1Kuro>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<+>|Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>|Sh3kbp1<tm1Kuro>|Cd79a<tm1(cre)Reth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6 * NZB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1a cell number
  http://purl.obolibrary.org/obo/MP_0008168

文献

http://purl.org/net/cito/citesAsAuthority

• Kohei. Kometani, et.al., CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway., The Journal of experimental medicine, 2011, 208
  http://rdf.ncbi.nlm.nih.gov/pubmed/21708930