increased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Spen<tm2.1Hon>/Spen<tm2.1Hon>

http://metadb.riken.jp/0008173I129P2OlaHsdC57BL6CBACd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonSpentm21HonSpentm21HonCd19tm1creCgnSpentm21HonRbpjtm1HonCd19

increased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Spen<tm2.1Hon>/Spen<tm2.1Hon>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SPEN homolog, transcriptional regulator (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891706
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• recombination signal binding protein for immunoglobulin kappa J region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96522

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Spen<tm2.1Hon>/Spen<tm2.1Hon>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Spen<tm2.1Hon>|Rbpj<tm1Hon>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008173

文献

http://purl.org/net/cito/citesAsAuthority

• Daisuke. Yabe, et.al., Generation of a conditional knockout allele for mammalian Spen protein Mint/SHARP., Genesis (New York, N.Y. : 2000), 2007, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/17457934