decreased follicular B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>

http://metadb.riken.jp/0008174B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd

decreased follicular B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dedicator of cyto-kinesis 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2149010
• interferon regulatory factor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1350924

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irf5<tm1Ttg>|Dock2<m1Hsd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6NHsd.Cg-Irf5<tm1Ttg> Dock2<m1Hsd>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Whitney E. Purtha, et.al., Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22431588