decreased follicular B cell number_Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0008174I129P2OlaHsd129S6SvEvTacC57BL6JGtROSA26Sortm2CAGNotch2UzsGtROSA26SorCd19tm1creCgnCd19Cd19tm1creCgnGtROSA26Sortm2CAGNotch2UzsGtROSA26SorCd19

decreased follicular B cell number_Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>|Gt(ROSA)26Sor<+>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Franziska. Hampel, et.al., CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling., Blood, 2011, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/21795747