increased germinal center B cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<+>,Pten<tm1Hwu>/Pten<+>,Tg(CD2-icre)4Kio/0

http://metadb.riken.jp/0008177I129S1Sv129S4SvJaeC57BL10CBACaBcl2l11tm11AstBcl2l11Ptentm1HwuPtenTgCD2icre4Kio0Ptentm1HwuPtenBcl2l11TgCD2icre4KioBcl2l11tm11Ast

increased germinal center B cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<+>,Pten<tm1Hwu>/Pten<+>,Tg(CD2-icre)4Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• BCL2-like 11 (apoptosis facilitator)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1197519
• transgene insertion 4, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449946

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl2l11<tm1.1Ast>/Bcl2l11<+>,Pten<tm1Hwu>/Pten<+>,Tg(CD2-icre)4Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Pten<+>|Bcl2l11<+>|Tg(CD2-icre)4Kio|Bcl2l11<tm1.1Ast>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008177

文献

http://purl.org/net/cito/citesAsAuthority

• Changchun. Xiao, et.al., Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18327259