decreased germinal center B cell number_Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

http://metadb.riken.jp/0008178I129P2OlaHsdC57BL6C57BL6JJclBcl6tm11MttoBcl6tm11MttoIghg1tm1creCgnIghg1Ighg1Ighg1tm1creCgnBcl6tm11Mtto

decreased germinal center B cell number_Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy constant gamma 1 (G1m marker)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96446
• B cell leukemia/lymphoma 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:107187

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ighg1<+>|Ighg1<tm1(cre)Cgn>|Bcl6<tm1.1Mtto>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Tomohiro. Kaji, et.al., Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory., The Journal of experimental medicine, 2012, 209
  http://rdf.ncbi.nlm.nih.gov/pubmed/23027924