decreased germinal center B cell number_Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008178IBALBcC57BL6C57BL6JJclDBA2Bcl6tm11MttoBcl6tm11MttoCd79atm1creRethCd79aTgCd4cre1Cwi0Cd79atm1creRethBcl6tm11MttoCd79aTgCd4cre1Cwi

decreased germinal center B cell number_Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• B cell leukemia/lymphoma 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:107187
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl6<tm1.1Mtto>/Bcl6<tm1.1Mtto>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<tm1(cre)Reth>|Bcl6<tm1.1Mtto>|Cd79a<+>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Tomohiro. Kaji, et.al., Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory., The Journal of experimental medicine, 2012, 209
  http://rdf.ncbi.nlm.nih.gov/pubmed/23027924