decreased germinal center B cell number_Sh2d1a<tm2Vei>/Sh2d1a<tm2Vei>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008178IC57BL6DBA2Sh2d1atm2VeiSh2d1atm2VeiTgCd4cre1Cwi0TgCd4cre1CwiSh2d1atm2Vei

decreased germinal center B cell number_Sh2d1a<tm2Vei>/Sh2d1a<tm2Vei>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm2Vei>/Sh2d1a<tm2Vei>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Sh2d1a<tm2Vei>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• André. Veillette, et.al., SAP expression in T cells, not in B cells, is required for humoral immunity., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18212118