increased marginal zone B cell number_Pik3cd<tm1Tnr>/Pik3cd<tm1Tnr>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0008181I129P2OlaHsd129S1Sv129S4SvJaeC57BL6Pik3cdtm1TnrPik3cdtm1TnrPtentm21PppPtentm21PppCd19tm1creCgnCd19Cd19Pik3cdtm1TnrPtentm21PppCd19tm1creCgn

increased marginal zone B cell number_Pik3cd<tm1Tnr>/Pik3cd<tm1Tnr>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098211

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3cd<tm1Tnr>/Pik3cd<tm1Tnr>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Pik3cd<tm1Tnr>|Pten<tm2.1Ppp>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008181

文献

http://purl.org/net/cito/citesAsAuthority

• Michelle L. Janas, et.al., The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18178811