decreased marginal zone B cell number_Nfkb2<tm2Brv>/Nfkb2<tm2Brv>,Tg(Tnfsf13b)1Fma/?

http://metadb.riken.jp/0008182B6CgNfkb2tm2BrvTgTnfsf13b1FmaNfkb2tm2BrvNfkb2tm2BrvTgTnfsf13b1FmaTgTnfsf13b1FmaNfkb2tm2Brv

decreased marginal zone B cell number_Nfkb2<tm2Brv>/Nfkb2<tm2Brv>,Tg(Tnfsf13b)1Fma/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Fabienne Mackay
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450863
• nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099800

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfkb2<tm2Brv>/Nfkb2<tm2Brv>,Tg(Tnfsf13b)1Fma/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tnfsf13b)1Fma|Nfkb2<tm2Brv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Nfkb2<tm2Brv> Tg(Tnfsf13b)1Fma

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008182

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas. Enzler, et.al., Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease., Immunity, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16973390