decreased marginal zone B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Notch2<tm1Hhi>/Notch2<+>

http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6CBACd19tm1creCgnCd19Notch2tm1HhiNotch2Cd19tm1creCgnNotch2Cd19Notch2tm1Hhi

decreased marginal zone B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Notch2<tm1Hhi>/Notch2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• notch 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97364

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Notch2<tm1Hhi>/Notch2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Notch2<+>|Cd19<+>|Notch2<tm1Hhi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008182

文献

http://purl.org/net/cito/citesAsAuthority

• Toshiki. Saito, et.al., Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development., Immunity, 2003, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/12753744