decreased marginal zone B cell number_Notch2<tm2Hhi>/Notch2<tm1Hhi>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008182IC57BL6CBANotch2tm2HhiNotch2tm1HhiTgMx1cre1Cgn0Notch2tm2HhiTgMx1cre1CgnNotch2tm1Hhi

decreased marginal zone B cell number_Notch2<tm2Hhi>/Notch2<tm1Hhi>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• notch 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97364

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch2<tm2Hhi>/Notch2<tm1Hhi>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Notch2<tm2Hhi>|Tg(Mx1-cre)1Cgn|Notch2<tm1Hhi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008182

文献

http://purl.org/net/cito/citesAsAuthority

• Toshiki. Saito, et.al., Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development., Immunity, 2003, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/12753744