absent B-1a cells_Btk<tm1Gsv>/Y,Tg(CD19-BTK*K430R)XK24Rwhe/?

http://metadb.riken.jp/0008203I129P2OlaHsdC57BL6FVBBtktm1GsvYTgCD19BTKK430RXK24RwheTgCD19BTKK430RXK24RwheBtktm1Gsv

absent B-1a cells_Btk<tm1Gsv>/Y,Tg(CD19-BTK*K430R)XK24Rwhe/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Bruton agammaglobulinemia tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88216
• transgene insertion XK24, Rudolf Hendriks
  http://metadb.riken.jp/db/mgi_rdf/MGI:3709261

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Btk<tm1Gsv>/Y,Tg(CD19-BTK*K430R)XK24Rwhe/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD19-BTK*K430R)XK24Rwhe|Btk<tm1Gsv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent B-1a cells
  http://purl.obolibrary.org/obo/MP_0008203

文献

http://purl.org/net/cito/citesAsAuthority

• Sabine. Middendorp, et.al., Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity., Journal of immunology (Baltimore, Md. : 1950), 2003, 171
  http://rdf.ncbi.nlm.nih.gov/pubmed/14634110