decreased pro-B cell number_Ikzf1<tm3.1Mbu>/Ikzf1<tm3.1Mbu>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>

http://metadb.riken.jp/0008208I129P2OlaHsd129SSvEvBALBcC57BL6SJLIkzf1tm31MbuIkzf1tm31MbuCd79atm1creRethCd79aRag2tm1FwaRag2tm1FwaCd79atm1creRethIkzf1tm31MbuCd79aRag2tm1Fwa

decreased pro-B cell number_Ikzf1<tm3.1Mbu>/Ikzf1<tm3.1Mbu>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• IKAROS family zinc finger 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342540
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ikzf1<tm3.1Mbu>/Ikzf1<tm3.1Mbu>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<tm1(cre)Reth>|Ikzf1<tm3.1Mbu>|Cd79a<+>|Rag2<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pro-B cell number
  http://purl.obolibrary.org/obo/MP_0008208

文献

http://purl.org/net/cito/citesAsAuthority

• Tanja A. Schwickert, et.al., Stage-specific control of early B cell development by the transcription factor Ikaros., Nature immunology, 2014, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/24509509