decreased pro-B cell number_Tet2<tm1Ics>/Tet2<tm1Ics>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008208IC57BL6CBATet2tm1IcsTet2tm1IcsTgMx1cre1Cgn0TgMx1cre1CgnTet2tm1Ics

decreased pro-B cell number_Tet2<tm1Ics>/Tet2<tm1Ics>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tet methylcytosine dioxygenase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443298
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tet2<tm1Ics>/Tet2<tm1Ics>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Tet2<tm1Ics>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pro-B cell number
  http://purl.obolibrary.org/obo/MP_0008208

文献

http://purl.org/net/cito/citesAsAuthority

• Cyril. Quivoron, et.al., TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis., Cancer cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21723201