decreased pre-B cell number_Blk<tm1Tara>/Blk<tm1Tara>,Fyn<tm1Sor>/Fyn<tm1Sor>,Lyn<tm1Ard>/Lyn<tm1Ard>

http://metadb.riken.jp/0008209EB6129Lyntm1ArdFyntm1SorBlktm1TaraorI129P2OlaHsd129S7SvEvBrdC57BL6Blktm1TaraBlktm1TaraFyntm1SorFyntm1SorLyntm1ArdLyntm1ArdFyntm1SorBlktm1TaraLyntm1Ard

decreased pre-B cell number_Blk<tm1Tara>/Blk<tm1Tara>,Fyn<tm1Sor>/Fyn<tm1Sor>,Lyn<tm1Ard>/Lyn<tm1Ard>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fyn proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95602
• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892
• B lymphoid kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Blk<tm1Tara>/Blk<tm1Tara>,Fyn<tm1Sor>/Fyn<tm1Sor>,Lyn<tm1Ard>/Lyn<tm1Ard>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fyn<tm1Sor>|Blk<tm1Tara>|Lyn<tm1Ard>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: B6.129-Lyn<tm1Ard> Fyn<tm1Sor> Blk<tm1Tara> or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pre-B cell number
  http://purl.obolibrary.org/obo/MP_0008209

文献

http://purl.org/net/cito/citesAsAuthority

• Kaoru. Saijo, et.al., Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development., Nature immunology, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/12563261