decreased pre-B cell number_Pknox1<tm2.1Fbla>/Pknox1<tm2.1Fbla>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0008209I129P2OlaHsdPknox1tm21FblaPknox1tm21FblaGtROSA26Sortm2creERT2BrnGtROSA26SorPknox1tm21FblaGtROSA26Sortm2creERT2BrnGtROSA26Sor

decreased pre-B cell number_Pknox1<tm2.1Fbla>/Pknox1<tm2.1Fbla>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• Pbx/knotted 1 homeobox
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pknox1<tm2.1Fbla>/Pknox1<tm2.1Fbla>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pknox1<tm2.1Fbla>|Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pre-B cell number
  http://purl.obolibrary.org/obo/MP_0008209

文献

http://purl.org/net/cito/citesAsAuthority

• Giorgio. Iotti, et.al., Reduction of Prep1 levels affects differentiation of normal and malignant B cells and accelerates Myc driven lymphomagenesis., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/23133585