decreased pre-B cell number_Mapk1<tm2Moga>/Mapk1<tm2Moga>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Mx1-cre)1Cgn/?

http://metadb.riken.jp/0008209I129Sv129P2OlaHsdC57BL6CBAMapk1tm2MogaMapk1tm2MogaMapk3tm1GpgMapk3tm1GpgTgMx1cre1CgnMapk1tm2MogaMapk3tm1GpgTgMx1cre1Cgn

decreased pre-B cell number_Mapk1<tm2Moga>/Mapk1<tm2Moga>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Mx1-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346859
• mitogen-activated protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346858
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk1<tm2Moga>/Mapk1<tm2Moga>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Tg(Mx1-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk1<tm2Moga>|Mapk3<tm1Gpg>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pre-B cell number
  http://purl.obolibrary.org/obo/MP_0008209

文献

http://purl.org/net/cito/citesAsAuthority

• Tomoharu. Yasuda, et.al., Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion., Immunity, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18356083