increased mature B cell number_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH1)2BJkbv/0,Tg(IGK@yK1)9.2CJkbv/0

http://metadb.riken.jp/0008210I129P2OlaHsdIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH12BJkbv0TgIGKyK192CJkbv0Igkctm1JkbvTgIGKyK192CJkbvTgIGHyH12BJkbvIghJtm1Jkbv

increased mature B cell number_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH1)2BJkbv/0,Tg(IGK@yK1)9.2CJkbv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 9.2C, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802673
• transgene insertion 2B, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802670
• immunoglobulin kappa constant
  http://metadb.riken.jp/db/mgi_rdf/MGI:96495
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH1)2BJkbv/0,Tg(IGK@yK1)9.2CJkbv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igkc<tm1Jkbv>|Tg(IGK@yK1)9.2CJkbv|Tg(IGH@yH1)2BJkbv|Igh-J<tm1Jkbv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008210

文献

http://purl.org/net/cito/citesAsAuthority

• L L. Green, et.al., Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs., Nature genetics, 1994, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/8075633