decreased mature B cell number_Igkrs<tm1Nemz>/Igkrs<tm1Nemz>,Tg(UBC-scFv)2Nemz/?

http://metadb.riken.jp/0008211I129C57BL6DBA2Igkrstm1NemzIgkrstm1NemzTgUBCscFv2NemzIgkrstm1NemzTgUBCscFv2Nemz

decreased mature B cell number_Igkrs<tm1Nemz>/Igkrs<tm1Nemz>,Tg(UBC-scFv)2Nemz/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, David Nemazee
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760407
• immunoglobulin kappa chain recombining segment
  http://metadb.riken.jp/db/mgi_rdf/MGI:96521

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igkrs<tm1Nemz>/Igkrs<tm1Nemz>,Tg(UBC-scFv)2Nemz/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igkrs<tm1Nemz>|Tg(UBC-scFv)2Nemz

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• José Luis. Vela, et.al., Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production., Immunity, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18261939