decreased mature B cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0008211I129S1SvBALBcBcl2l11tm11AstBcl2l11tm11AstDicer1tm1MmkDicer1tm1MmkCd79atm1creRethCd79aCd79aBcl2l11tm11AstCd79atm1creRethDicer1tm1Mmk

decreased mature B cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• BCL2-like 11 (apoptosis facilitator)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1197519
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<+>|Bcl2l11<tm1.1Ast>|Cd79a<tm1(cre)Reth>|Dicer1<tm1Mmk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• Sergei B. Koralov, et.al., Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage., Cell, 2008, 132
  http://rdf.ncbi.nlm.nih.gov/pubmed/18329371