decreased mature B cell number_Ggta1<tm1Jbl>/Ggta1<+>,Igh<tm1Jiac>/Igh<tm1Jiac>,Igk<tm1Jiac>/Igk<+>

http://metadb.riken.jp/0008211I129S2SvPas129S4SvJaeC57BL6Ggta1tm1JblGgta1Ightm1JiacIghtm1JiacIgktm1JiacIgkIghtm1JiacIgkGgta1tm1JblGgta1Igktm1Jiac

decreased mature B cell number_Ggta1<tm1Jbl>/Ggta1<+>,Igh<tm1Jiac>/Igh<tm1Jiac>,Igk<tm1Jiac>/Igk<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• immunoglobulin kappa chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96494
• glycoprotein galactosyltransferase alpha 1, 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95704

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ggta1<tm1Jbl>/Ggta1<+>,Igh<tm1Jiac>/Igh<tm1Jiac>,Igk<tm1Jiac>/Igk<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm1Jiac>|Igk<+>|Ggta1<tm1Jbl>|Ggta1<+>|Igk<tm1Jiac>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• Lorenzo. Benatuil, et.al., Ig knock-in mice producing anti-carbohydrate antibodies: breakthrough of B cells producing low affinity anti-self antibodies., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18322191