decreased mature B cell number_Gt(ROSA)26Sor<tm1Jus>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008211IC57BL6C57BL6JC57BL6NCBAGtROSA26Sortm1JusGtROSA26SorTgMx1cre1Cgn0TgMx1cre1CgnGtROSA26SorGtROSA26Sortm1Jus

decreased mature B cell number_Gt(ROSA)26Sor<tm1Jus>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Jus>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1Jus>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• Brandi L. Carofino, et.al., A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL)., Disease models & mechanisms, 2013, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/24046360