decreased immature B cell number_Nfkbia<tm1Bal>/Nfkbia<tm1Bal>,Nfkbie<tm1Syme>/Nfkbie<tm1Syme>

http://metadb.riken.jp/0008215I129P2OlaHsd129S4SvJaeC57BL6DBA2Nfkbiatm1BalNfkbiatm1BalNfkbietm1SymeNfkbietm1SymeNfkbiatm1BalNfkbietm1Syme

decreased immature B cell number_Nfkbia<tm1Bal>/Nfkbia<tm1Bal>,Nfkbie<tm1Syme>/Nfkbie<tm1Syme>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104741
• nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
  http://metadb.riken.jp/db/mgi_rdf/MGI:1194908

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfkbia<tm1Bal>/Nfkbia<tm1Bal>,Nfkbie<tm1Syme>/Nfkbie<tm1Syme>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nfkbia<tm1Bal>|Nfkbie<tm1Syme>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased immature B cell number
  http://purl.obolibrary.org/obo/MP_0008215

文献

http://purl.org/net/cito/citesAsAuthority

• Bertrand. Goudeau, et.al., IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14665694