decreased immature B cell number_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

http://metadb.riken.jp/0008215I129P2OlaHsdIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231JkbvTgIGKyK2J231JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92JkbvIgkctm1Jkbv

decreased immature B cell number_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa constant
  http://metadb.riken.jp/db/mgi_rdf/MGI:96495
• transgene insertion J9.2, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802719
• transgene insertion J23.1, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802720
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh-J<tm1Jkbv>|Tg(IGK@yK2)J23.1Jkbv|Tg(IGH@yH2)J9.2Jkbv|Igkc<tm1Jkbv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased immature B cell number
  http://purl.obolibrary.org/obo/MP_0008215

文献

http://purl.org/net/cito/citesAsAuthority

• L L. Green, et.al., Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes., The Journal of experimental medicine, 1998, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/9687526