increased susceptibility to neuronal excitotoxicity_Tg(YAC128)55Hay/Tg(YAC128)55Hay

http://metadb.riken.jp/0008235FVBNTgYAC12855HayTgYAC12855HayTgYAC12855HayTgYAC12855Hay

increased susceptibility to neuronal excitotoxicity_Tg(YAC128)55Hay/Tg(YAC128)55Hay

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 55, Michael Hayden
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432146

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(YAC128)55Hay/Tg(YAC128)55Hay

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(YAC128)55Hay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(YAC128)55Hay

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to neuronal excitotoxicity
  http://purl.obolibrary.org/obo/MP_0008235

文献

http://purl.org/net/cito/citesAsAuthority

• Rona K. Graham, et.al., Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models., Neurobiology of disease, 2006, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/16230019
• Jacqueline. Shehadeh, et.al., Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease., Neurobiology of disease, 2006, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/16165367