increased susceptibility to neuronal excitotoxicity_Psen1<tm1Mpm>/Psen1<tm1Mpm>

http://metadb.riken.jp/0008235I129S1Sv129X1SvJC57BL6Psen1tm1MpmPsen1tm1MpmPsen1tm1Mpm

increased susceptibility to neuronal excitotoxicity_Psen1<tm1Mpm>/Psen1<tm1Mpm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm1Mpm>/Psen1<tm1Mpm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<tm1Mpm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to neuronal excitotoxicity
  http://purl.obolibrary.org/obo/MP_0008235

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Guo, et.al., Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice., Nature medicine, 1999, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/9883847