decreased susceptibility to neuronal excitotoxicity_Gt(ROSA)26Sor<tm1(Crh)Jde>/Gt(ROSA)26Sor<tm1(Crh)Jde>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0008236I129S2SvPasC57BL6SJLGtROSA26Sortm1CrhJdeGtROSA26Sortm1CrhJdeTgNescre1Kln0GtROSA26Sortm1CrhJdeTgNescre1Kln

decreased susceptibility to neuronal excitotoxicity_Gt(ROSA)26Sor<tm1(Crh)Jde>/Gt(ROSA)26Sor<tm1(Crh)Jde>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Crh)Jde>/Gt(ROSA)26Sor<tm1(Crh)Jde>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Crh)Jde>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to neuronal excitotoxicity
  http://purl.obolibrary.org/obo/MP_0008236

文献

http://purl.org/net/cito/citesAsAuthority

• R. Hanstein, et.al., Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress., Neuroscience, 2008, 156
  http://rdf.ncbi.nlm.nih.gov/pubmed/18708129