abnormal macrophage derived foam cell morphology_Apoe<tm1Unc>/Apoe<tm1Unc>,Hsd11b1<tm1Lex>/Hsd11b1<tm1Lex>

http://metadb.riken.jp/0008243B6129Hsd11b1tm1LexApoetm1UncApoetm1UncApoetm1UncHsd11b1tm1LexHsd11b1tm1LexHsd11b1tm1LexApoetm1Unc

abnormal macrophage derived foam cell morphology_Apoe<tm1Unc>/Apoe<tm1Unc>,Hsd11b1<tm1Lex>/Hsd11b1<tm1Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hydroxysteroid 11-beta dehydrogenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103562
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Hsd11b1<tm1Lex>/Hsd11b1<tm1Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hsd11b1<tm1Lex>|Apoe<tm1Unc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Hsd11b1<tm1Lex> Apoe<tm1Unc>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal macrophage derived foam cell morphology
  http://purl.obolibrary.org/obo/MP_0008243

文献

http://purl.org/net/cito/citesAsAuthority

• Ricardo A. García, et.al., 11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/23383297