increased megakaryocyte cell number_Gt(ROSA)26Sor<tm1(CAG-NPM1*)Geno>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008254IC57BL6CBAGtROSA26Sortm1CAGNPM1GenoGtROSA26SorTgMx1cre1Cgn0GtROSA26Sortm1CAGNPM1GenoTgMx1cre1CgnGtROSA26Sor

increased megakaryocyte cell number_Gt(ROSA)26Sor<tm1(CAG-NPM1*)Geno>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-NPM1*)Geno>/Gt(ROSA)26Sor<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(CAG-NPM1*)Geno>|Tg(Mx1-cre)1Cgn|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased megakaryocyte cell number
  http://purl.obolibrary.org/obo/MP_0008254

文献

http://purl.org/net/cito/citesAsAuthority

• Paolo. Sportoletti, et.al., The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model., Blood, 2013, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/23435463