abnormal autophagy_Tsc2<tm1Djk>/Tsc2<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Camk2a-cre)T29-1Stl/0

http://metadb.riken.jp/0008260I129S4SvJaeBALBcC57BLC57BL6CBAJNCrljTsc2tm1DjkTsc2Atg7tm1TchiAtg7tm1TchiTgCamk2acreT291Stl0Tsc2Tsc2tm1DjkTgCamk2acreT291StlAtg7tm1Tchi

abnormal autophagy_Tsc2<tm1Djk>/Tsc2<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Camk2a-cre)T29-1Stl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• autophagy related 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921494
• tuberous sclerosis 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102548
• transgene insertion T29-1, Susumu Tonegawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177646

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tsc2<tm1Djk>/Tsc2<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Camk2a-cre)T29-1Stl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tsc2<+>|Tsc2<tm1Djk>|Tg(Camk2a-cre)T29-1Stl|Atg7<tm1Tchi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL * C57BL/6 * CBA/JNCrlj

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal autophagy
  http://purl.obolibrary.org/obo/MP_0008260

文献

http://purl.org/net/cito/citesAsAuthority

• Guomei. Tang, et.al., Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits., Neuron, 2014, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/25155956