abnormal hippocampus CA3 region morphology_Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(Thy1-APPSwDutIowa)BWevn/?

http://metadb.riken.jp/0008267IC57BL6Nos2tm1LauNos2tm1LauTgThy1APPSwDutIowaBWevnNos2tm1LauTgThy1APPSwDutIowaBWevn

abnormal hippocampus CA3 region morphology_Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(Thy1-APPSwDutIowa)BWevn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion B, William E Van Nostrand
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721991
• nitric oxide synthase 2, inducible
  http://metadb.riken.jp/db/mgi_rdf/MGI:97361

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(Thy1-APPSwDutIowa)BWevn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nos2<tm1Lau>|Tg(Thy1-APPSwDutIowa)BWevn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hippocampus CA3 region morphology
  http://purl.obolibrary.org/obo/MP_0008267

文献

http://purl.org/net/cito/citesAsAuthority

• Carol A. Colton, et.al., The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP., Journal of Alzheimer's disease : JAD, 2008, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19096157
• Donna M. Wilcock, et.al., Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18272675