abnormal bone ossification_Lrp5<tm1.1Vari>/Lrp5<tm1.1Vari>,Lrp6<tm1.1Vari>/Lrp6<tm1.1Vari>,Twist2<tm1(cre)Dor>/Twist2<+>

http://metadb.riken.jp/0008271I129S1Sv129X1SvJLrp5tm11VariLrp5tm11VariLrp6tm11VariLrp6tm11VariTwist2tm1creDorTwist2Lrp6tm11VariTwist2Twist2tm1creDorLrp5tm11Vari

abnormal bone ossification_Lrp5<tm1.1Vari>/Lrp5<tm1.1Vari>,Lrp6<tm1.1Vari>/Lrp6<tm1.1Vari>,Twist2<tm1(cre)Dor>/Twist2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor-related protein 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298218
• twist basic helix-loop-helix transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104685
• low density lipoprotein receptor-related protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1278315

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrp5<tm1.1Vari>/Lrp5<tm1.1Vari>,Lrp6<tm1.1Vari>/Lrp6<tm1.1Vari>,Twist2<tm1(cre)Dor>/Twist2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp6<tm1.1Vari>|Twist2<+>|Twist2<tm1(cre)Dor>|Lrp5<tm1.1Vari>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal bone ossification
  http://purl.obolibrary.org/obo/MP_0008271

文献

http://purl.org/net/cito/citesAsAuthority

• Kyu Sang. Joeng, et.al., Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo., Developmental biology, 2011, 359
  http://rdf.ncbi.nlm.nih.gov/pubmed/21924256