abnormal intramembranous bone ossification_Gt(ROSA)26Sor<tm1(PDGFRA*)Hsc>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0008273I129SvC57BL6CBAGtROSA26Sortm1PDGFRAHscGtROSA26SorTgWnt1cre11Rth0TgWnt1cre11RthGtROSA26SorGtROSA26Sortm1PDGFRAHsc

abnormal intramembranous bone ossification_Gt(ROSA)26Sor<tm1(PDGFRA*)Hsc>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(PDGFRA*)Hsc>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(PDGFRA*)Hsc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal intramembranous bone ossification
  http://purl.obolibrary.org/obo/MP_0008273

文献

http://purl.org/net/cito/citesAsAuthority

• Anne. Moenning, et.al., Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047372