failure of endochondral bone ossification_Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Col11a2-cre)1Ntsu/0

http://metadb.riken.jp/0008275IC57BLC57BL6CBAJNCrljDBA2Sp7tm1RnisSp7tm1RnisTgCol11a2cre1Ntsu0TgCol11a2cre1NtsuSp7tm1Rnis

failure of endochondral bone ossification_Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Col11a2-cre)1Ntsu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Noriyuki Tsumaki
  http://metadb.riken.jp/db/mgi_rdf/MGI:5435237
• Sp7 transcription factor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:2153568

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Col11a2-cre)1Ntsu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col11a2-cre)1Ntsu|Sp7<tm1Rnis>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * C57BL/6 * CBA/JNCrlj * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• failure of endochondral bone ossification
  http://purl.obolibrary.org/obo/MP_0008275

文献

http://purl.org/net/cito/citesAsAuthority

• Riko. Nishimura, et.al., Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22869368