failure of endochondral bone ossification_Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Prrx1-cre)1Cjt/0

http://metadb.riken.jp/0008275IC57BLC57BL6CBAJNCrljSJLJSp7tm1RnisSp7tm1RnisTgPrrx1cre1Cjt0Sp7tm1RnisTgPrrx1cre1Cjt

failure of endochondral bone ossification_Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Prrx1-cre)1Cjt/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Sp7 transcription factor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:2153568
• transgene insertion 1, Clifford J Tabin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450928

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sp7<tm1Rnis>/Sp7<tm1Rnis>,Tg(Prrx1-cre)1Cjt/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sp7<tm1Rnis>|Tg(Prrx1-cre)1Cjt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• failure of endochondral bone ossification
  http://purl.obolibrary.org/obo/MP_0008275

文献

http://purl.org/net/cito/citesAsAuthority

• Riko. Nishimura, et.al., Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22869368