abnormal hippocampus pyramidal cell layer_Psen1<tm1Lpr>/Psen1<tm1Lpr>,Tg(Thy1-APP<SL>)28Lpr/0

http://metadb.riken.jp/0008284E129SvorI129SvC57BL6Psen1tm1LprPsen1tm1LprTgThy1APPSL28Lpr0Psen1tm1LprTgThy1APPSL28Lpr

abnormal hippocampus pyramidal cell layer_Psen1<tm1Lpr>/Psen1<tm1Lpr>,Tg(Thy1-APP<SL>)28Lpr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717
• transgene insertion 28, Laurent Pradier
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510602

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm1Lpr>/Psen1<tm1Lpr>,Tg(Thy1-APP<SL>)28Lpr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<tm1Lpr>|Tg(Thy1-APP<SL>)28Lpr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: 129/Sv or (involves: 129/Sv * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hippocampus pyramidal cell layer
  http://purl.obolibrary.org/obo/MP_0008284

文献

http://purl.org/net/cito/citesAsAuthority

• Caty. Casas, et.al., Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model., The American journal of pathology, 2004, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/15466394