increased somatotroph cell number_Emx1<tm1(cre)Ito>/Emx1<+>,Hes1<tm1Fgu>/Hes1<tm1Hojo>,Hes5<tm1Fgu>/Hes5<tm1Fgu>

http://metadb.riken.jp/0008328I129P2OlaHsd129S1Sv129X1SvJEmx1tm1creItoEmx1Hes1tm1FguHes1tm1HojoHes5tm1FguHes5tm1FguEmx1tm1creItoHes1tm1FguHes1tm1HojoHes5tm1FguEmx1

increased somatotroph cell number_Emx1<tm1(cre)Ito>/Emx1<+>,Hes1<tm1Fgu>/Hes1<tm1Hojo>,Hes5<tm1Fgu>/Hes5<tm1Fgu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hairy and enhancer of split 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104853
• hairy and enhancer of split 5 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104876
• empty spiracles homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Emx1<tm1(cre)Ito>/Emx1<+>,Hes1<tm1Fgu>/Hes1<tm1Hojo>,Hes5<tm1Fgu>/Hes5<tm1Fgu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Emx1<tm1(cre)Ito>|Hes1<tm1Fgu>|Hes1<tm1Hojo>|Hes5<tm1Fgu>|Emx1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased somatotroph cell number
  http://purl.obolibrary.org/obo/MP_0008328

文献

http://purl.org/net/cito/citesAsAuthority

• Aya. Kita, et.al., Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development., Molecular endocrinology (Baltimore, Md.), 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17426285