abnormal osteoblast differentiation_Gt(ROSA)26Sor<tm3(Runx2)Flng>/Gt(ROSA)26Sor<tm3(Runx2)Flng>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

http://metadb.riken.jp/0008395I129S1Sv129X1SvJGtROSA26Sortm3Runx2FlngGtROSA26Sortm3Runx2FlngIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcTgCol2a1cre3AmcGtROSA26Sortm3Runx2Flng

abnormal osteoblast differentiation_Gt(ROSA)26Sor<tm3(Runx2)Flng>/Gt(ROSA)26Sor<tm3(Runx2)Flng>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Indian hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96533
• transgene insertion 3, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176260
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm3(Runx2)Flng>/Gt(ROSA)26Sor<tm3(Runx2)Flng>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ihh<tm1Amc>|Tg(Col2a1-cre)3Amc|Gt(ROSA)26Sor<tm3(Runx2)Flng>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal osteoblast differentiation
  http://purl.obolibrary.org/obo/MP_0008395

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaolin. Tu, et.al., Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation., Developmental biology, 2012, 362
  http://rdf.ncbi.nlm.nih.gov/pubmed/22155527