decreased cellular sensitivity to ultraviolet irradiation_Shc1<tm1Pgp>/Shc1<tm1Pgp>

http://metadb.riken.jp/0008411I129SvShc1tm1PgpShc1tm1PgpShc1tm1Pgp

decreased cellular sensitivity to ultraviolet irradiation_Shc1<tm1Pgp>/Shc1<tm1Pgp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• src homology 2 domain-containing transforming protein C1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98296

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shc1<tm1Pgp>/Shc1<tm1Pgp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shc1<tm1Pgp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cellular sensitivity to ultraviolet irradiation
  http://purl.obolibrary.org/obo/MP_0008411

文献

http://purl.org/net/cito/citesAsAuthority

• Claudio. Napoli, et.al., Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12571362
• E. Migliaccio, et.al., The p66shc adaptor protein controls oxidative stress response and life span in mammals., Nature, 1999, 402
  http://rdf.ncbi.nlm.nih.gov/pubmed/10580504