abnormal spatial working memory_Psen1<tm3.1Shn>/Psen1<tm3.1Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>

http://metadb.riken.jp/0008428I129C57BL6C57BL6JCBAPsen1tm31ShnPsen1tm31ShnPsen2tm1HaaPsen2tm1HaaPsen1tm31ShnPsen2tm1Haa

abnormal spatial working memory_Psen1<tm3.1Shn>/Psen1<tm3.1Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109284
• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm3.1Shn>/Psen1<tm3.1Shn>,Psen2<tm1Haa>/Psen2<tm1Haa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<tm3.1Shn>|Psen2<tm1Haa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spatial working memory
  http://purl.obolibrary.org/obo/MP_0008428

文献

http://purl.org/net/cito/citesAsAuthority

• Hirotaka. Watanabe, et.al., Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22496554