abnormal spatial working memory_Syngap1<tm2Geno>/Syngap1<+>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0008428I129S2SvPasC57BL6CBASyngap1tm2GenoSyngap1TgCAGcreEsr15Amc0Syngap1tm2GenoTgCAGcreEsr15AmcSyngap1

abnormal spatial working memory_Syngap1<tm2Geno>/Syngap1<+>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• synaptic Ras GTPase activating protein 1 homolog (rat)
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039785

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Syngap1<tm2Geno>/Syngap1<+>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Syngap1<tm2Geno>|Tg(CAG-cre/Esr1*)5Amc|Syngap1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spatial working memory
  http://purl.obolibrary.org/obo/MP_0008428

文献

http://purl.org/net/cito/citesAsAuthority

• James P. Clement, et.al., Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses., Cell, 2012, 151
  http://rdf.ncbi.nlm.nih.gov/pubmed/23141534