abnormal cutaneous collagen fibril morphology_Fbn1<Tsk>/Fbn1<+>,Tgfb1<tm1N>/Tgfb1<+>

http://metadb.riken.jp/0008438I129SSvEvC57BL6JC57BL10DBA2Fbn1TskFbn1Tgfb1tm1NTgfb1Tgfb1tm1NFbn1Tgfb1Fbn1Tsk

abnormal cutaneous collagen fibril morphology_Fbn1<Tsk>/Fbn1<+>,Tgfb1<tm1N>/Tgfb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibrillin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95489
• transforming growth factor, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98725

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbn1<Tsk>/Fbn1<+>,Tgfb1<tm1N>/Tgfb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfb1<tm1N>|Fbn1<+>|Tgfb1<+>|Fbn1<Tsk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6J * C57BL/10 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cutaneous collagen fibril morphology
  http://purl.obolibrary.org/obo/MP_0008438

文献

http://purl.org/net/cito/citesAsAuthority

• T. McGaha, et.al., Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes., The Journal of investigative dermatology, 2001, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/11168809