absent spleen germinal center_Tnf<tm1Gkl>/Tnf<tm1Gkl>

http://metadb.riken.jp/0008474I129SSvEvC57BL6Tnftm1GklTnftm1GklTnftm1Gkl

absent spleen germinal center_Tnf<tm1Gkl>/Tnf<tm1Gkl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104798

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnf<tm1Gkl>/Tnf<tm1Gkl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnf<tm1Gkl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent spleen germinal center
  http://purl.obolibrary.org/obo/MP_0008474

文献

http://purl.org/net/cito/citesAsAuthority

• M. Pasparakis, et.al., Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response., The Journal of experimental medicine, 1996, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/8879212
• Lena. Alexopoulou, et.al., Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity., European journal of immunology, 2006, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/16983719